Human Sera
Cayman Chemical 4 DImethylamIno1methylpyr 50mg
A pyridinium salt with anticholinesterase and antiproliferative activities; inhibits cholinesterase activity in rat brain homogenates (Kd = 33 μM); inhibits and yeast ChoK (IC50 = 17 μM); has antiproliferative activity against HT-29 colon cancer cells (IC50 = 2 μM)
Cayman Chemical BD 1008hydrobromIde 50mg
A selective antagonist of the σ1 receptor (Ki = 2 nM) that displays 4-fold selectivity for σ1 over σ2; used to modulate signaling through σ receptors by cocaine and in models of learning and memory impairment
Cayman Chemical LPhenylephrInhydrochLRId 50mg
An adrenergic α1A receptor agonist (Ki = 1.4 µM) that demonstrates selectivity against the α1B and α1C receptor subtypes (Kis = 23.9 and 47.8 µM, respectively); frequently used to precontract smooth muscle in preparations designed to study the properties of various vasodilator agents
Cayman Chemical KnamycIn B 100mg
An aminoglycoside antibiotic; active against S. aureus, E. coli, P. aeruginosa, and P. rettgeri(MICs = 0.78-25 UG/ml); binds to the ribosomal decoding A site to interfere with bacterial protein synthesis
Cayman Chemical Capsacn 100mg
A terpene alkaloid; induces inward currents in HEK293 cells expressing rat TRPV1 (EC50 = 0.64 µM at neutral pH); decreases LPS-induced PGE2 production, as well as reduces LPS- and IFN-induced NO release in isolated mouse peritoneal macrophages at 10 and 50 µM; induces substance P release in rat spinal cord slices (EC50 = 2.3 µM); reduces acetylcholine- or phenylquinone-induced writhing (ED50s = 1.33 and 1.38 mg/kg, respectively, s.c.) but has no effect on the latency to paw withdrawal in the hot plate test in mice (ED50 = >20 mg/kg, s.c.)
Cayman Chemical GC7sulfate 50mg
A deoxyhypusine synthase inhibitor (Ki = 9.7 nM); inhibits the production of hypusine in CHO cells at 1 µM; inhibits activation of eIF5A2 and enhances the cytotoxicity of doxorubicin in Huh7 and HepG2 cells at 20 µM; reduces tumor growth in a Melan-a Tm5 murine melanoma model at 0.9 mg/kg
Cayman Chemical Dextromethorphn 50mg
An analytical reference standard categorized as an antitussive; has analgesic and anticonvulsant activities in rodents; has been found as an adulterant in 3,4-MDMA; has potential for abuse; intended for research and forensic applications
American Research Products Inc Human 6 hydroXymelatonin sulfa
Human 6-hydroXymelatonin sulfate (6HMS) ELISA kit from CUSABIO Detection Range 10 pg/mL- 400 pg/mL Sensitivity 10 pg/mL Sample serum plasma tissue homogenates Method Competitive
Cayman Chemical RIvastIgmIntartrate 100mg
A ChE inhibitor that inhibits BChE and AChE (IC50s = 0.037 and 4.15 μM, respectively); increases levels of sAPP and decreases levels of soluble amyloid-β (1-40) and various N-terminal cleavage products in primary embryonic rat neurons undergoing degeneration at 5 and 10 μM; inhibits formation of amyloid plaques in brain sections and increases in AChE, IL-1β, and BACE1 mRNA expression in the cerebral cortex at 1 mg/kg per day in a rat model of Alzheimer's disease induced by AlCl3; inhibits AlCl3-induced increases in escape latency time in the Morris water maze in a rat model of Alzheimer's disease at 1 mg/kg; reverses decreases in time spent in the open arms of an elevated plus maze, exploration time of a novel object in a novel object recognition test, and sucrose intake in a rat model of chronic mild stress at 2 mg/kg
Cayman Chemical BuclIzInhydrochlorIde 50mg
An antihistamine; reduces bronchoconstriction and lethality induced by aerosolized histamine in guinea pigs at 1 mg/kg; induces gross malformations and bone malformations in rats from 40-200 mg/kg; inhibits cancer cell growth by binding to TCTP and inducing cell differentiation
Cayman Chemical DeXromethorphnhydrobromId 50mg
An analytical reference standard categorized as an antitussive; has analgesic and anticonvulsant activities in rodents; has been found as an adulterant in 3,4-MDMA; has potential for abuse; intended for research and forensic applications
Cayman Chemical R-DeprenylhydrochlorIde 100mg
A selective, reversible inhibitor of MAO-B (Ki = 0.091 μM) over MAO-A (Ki = 9.06 μM); may ameliorate depression, Parkinson’s disease, Alzheimer’s disease, Huntington’s disease, and stroke
Cayman Chemical TIloronhydrochlorIde 50mg
An orally active, antiviral compound that induces interferon production and is reported to have antitumor, anti-inflammatory, and neuroprotective actions
Cayman Chemical TroglItazon 50mg
A selective agonist of PPARγ (EC50s = 0.78 and 0.55 μM for the mouse and human receptors, respectively, in a transactivation assay); selective for PPARγ over PPARα and PPARδ, at which it is inactive at ≤10 μM; exhibits antihyperglycemic and antihyperlipidemic properties in Zucker diabetic fatty rats, reducing plasma glucose and triglyceride levels by 61 and 87% respectively, at 500 mg/kg twice per day; induces cell cycle arrest at the G1 phase in SK-HEP-1 and Hep3B hepatocellular carcinoma cells at 10 μM and increases apoptosis in these cells at ≥30 μM